Thursday, July 28, 2016
Wednesday, July 27, 2016
Tuesday, July 26, 2016
Marijuana compound removes toxic Alzheimer's protein from the brain
30 JUN 2016
An active compound in marijuana called tetrahydrocannabinol (THC) has been found to promote the removal of toxic clumps of amyloid beta protein in the brain, which are thought to kickstart the progression of Alzheimer's disease.
The finding supports the results of previous studies that found evidence of the protective effects of cannabinoids, including THC, on patients with neurodegenerative disease.
"Although other studies have offered evidence that cannabinoids might be neuroprotective against the symptoms of Alzheimer's, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells," says one of the team, David Schubert from the Salk Institute for Biological Studies in California.
Schubert and his colleagues tested the effects of THC on human neurons grown in the lab that mimic the effects of Alzheimer's disease.
If you’re not familiar with this special little compound, it’s not only responsible for the majority of marijuana's psychological effects - including the high - thanks to its natural pain-relieving properties, it’s also been touted as an effective treatment for the symptoms of everything from HIV and chemotherapy to chronic pain, post traumatic stress disorder, and stroke.
In fact, THC appears to be such an amazing medical agent, researchers are working on breeding genetically modified yeast that can produce it way more efficiently than it would be to make synthetic versions.
The compound works by passing from the lungs to the bloodstream, where it attaches to two types of receptors, cannabinoid receptor (CB) 1 and 2, which are found on cell surfaces all over the body.
In the brain, these receptors are most concentrated in neurons associated with pleasure, memory, thinking, coordination and time perception, and usually bind with a class of lipid molecules called endocannabinoids that are produced by the body during physical activity to promote cell-to-cell signalling in the brain.
But THC can also bind to them in much the same way, and when they do, they start messing with your brain’s ability to communicate with itself. The can be a good and a bad thing, because while you might forget something important or suddenly be incapable of swinging a baseball bat, you’ll probably feel amazing, and want to eat all the snacks.
Over the years, research has suggested that by binding to these receptors, THC could be having another effect on ageing brains, because it appears to helps the body clear out the toxic accumulations - or 'plaques' - of amyloid beta.
No one’s entirely sure what causes Alzheimer’s disease, but it’s thought to result from a build-up of two types of lesions: amyloid plaques and neurofibrillary tangles.
Amyloid plaques sit between the neurons as dense clusters of beta-amyloid molecules - a sticky type of protein that easily clumps together - and neurofibrillary tangles are caused by defective tau proteins that clump up into a thick, insoluble mass in the neurons.
It’s not clear why these lesions begin to appear in the brain, but studies have linked inflammation in the brain tissue to the proliferation of plaques and neurofibrillary tangles. So if we can find something that eases brain inflammation while at the same time encourages the body to clear out these lesions, we could be on the way to finding the first effective treatment for Alzheimer’s ever.
Back in 2006, researchers at the Scripps Research Institute found that THC inhibits the formation of amyloid plaques by blocking the enzyme in the brain that produces them, and now Schubert and his team have demonstrated that it can also eliminate a dangerous inflammatory response from the nerve cells, ensuring their survival.
"Inflammation within the brain is a major component of the damage associated with Alzheimer's disease, but it has always been assumed that this response was coming from immune-like cells in the brain, not the nerve cells themselves," says one of the team, Antonio Currais.
"When we were able to identify the molecular basis of the inflammatory response to amyloid beta, it became clear that THC-like compounds that the nerve cells make themselves may be involved in protecting the cells from dying."
It's exciting stuff, but it's so far only been demonstrated in neurons in the lab, so the next step will be for Schubert and his team to observe the link between THC and reduced inflammation and plaque build-up in a clinical trial. And they've reportedly already found a drug candidate called J147 that appears to have the same effects as THC, so this might be the way they can test the effects of THC without the government getting in the way.
The results have been published in Aging and Mechanisms of Disease.
Sunday, July 24, 2016
|The Jewish Monopoly on Opium Still Fuels Chinese Resentment Today|
|The Beginning of the Opium Trade|
|Armed with this knowledge, he sailed back to England to make a new proposition to the Queen. And, on the advice of David Sassoon, Queen Victoria decided to export opium from the Indian Subcontinent to China where her military would enforce its importation and use.|
In Order to boost the trade David Sassoon forced the farmers in Bengali to stop farming food and turn to growing opium poppies. The climate in Bengali was very good for growing opium and Sassoon's business flourished. He became a member of the East India Company, a firm owned and run by Jews out of the City of London. So successful was the opium business that the tax the East Indian Company paid to England paid for all English wars between 1831 and 1905.
Opium Was a "Jewish Business"
The Jewish Encyclopedia of 1905 states that Sassoon expanded his opium trade into China and Japan. He placed his eight sons in charge of the various major opium exchanges in China.
According to the 1944 Jewish Encyclopedia: "He employed only Jews in his business, and wherever he sent them he built synagogues and schools for them. He imported whole families of fellow Jews. . . and put them to work."
Sassoon's sons were busy pushing this mind-destroying drug in Canton, China, and their trade expanded alarmingly. Between 1830 - 1831 they trafficked 18,956 chests of opium earning millions of dollars. Part of the profits went to Queen Victoria and the British government. In the year 1836 the trade increased to over 30,000 chests and drug addiction in coastal cities became endemic.
|The corrupt British monarchy honored them with privilege and knighthood - to the disgrace of the Crown. To this day the Sassoons are in the history books as "great developers" of India, but the source of their vast wealth is never mentioned - the destruction and impoverishment of the population of China.|
According to a 1930s edition of Fortune Magazine (USA), the Sassoon Family monopolized more than 70% of the opium trade and controlled every nook and corner of opium traffic between India and China. This is also consistent with research and observations according to Edward LeFevour in "Western Enterprise in Late Ch'ing Dynasty China". According to these sources, in the middle 1800s, the Sassoon group was acknowledged to be the major holder (more than 70%) of all opium stocks in India and in China.
|And Then The Opium Wars - Euphemistically called "The Boxer Rebellion"|
China's government, not too surprisingly, objected to the large-scale importation of narcotics into their country by a foreign power, provoking Britain to declare war.
In 1839, the Manchu Emperor ordered that it be stopped. He named the Commissioner of Canton, Lin Tse-hsu, to lead a campaign against opium. Lin seized 2,000 chests of Sassoon opium and threw it into the river. An outraged David Sassoon demanded that Great Britain retaliate. And because the Sassoon family had married into the Rothschild family who controlled the English economy, this demand had powerful Jewish backers in England.
Thus, the Opium Wars began with the British Army fighting as mercenaries of the Sassoons. They attacked cities and blockaded ports. The Chinese Army, decimated by 10 years of rampant opium addiction, proved no match for the British Army. The war ended in 1839 with the signing of "The Treaty of Nanking." This included provisions especially designed to guarantee the Sassoons the right to enslave an entire population with opium. The "peace treaty" included these provisions:
The Sassoons Use the British Army to Drug An Entire Nation
British Prime Minister Palmerston wrote Crown Commissiner Captain Charles Elliot that the treaty didn't go far enough. He said it should have been rejected out of hand because: "After all, our naval power is so strong that we can tell the Emperor what we mean to hold rather than what he would cede. We must demand the admission of opium into China's interior as an article of lawful commerce and increase the indemnity payments and British access to several additional Chinese ports."
Thus, China not only had to pay Sassoon the cost of his dumped opium, but reimburse England an unheard sum of 21 million pounds for the cost of the war!
This gave the Sassoon's monopoly rights to distribute opium in port cities. However, even this was not good enough and Sassoon demanded the right to sell opium throughout the nation. The Manchus resisted and the British Army again attacked in the Second Opium War fought 1858 - 1860. Palmerston declared that all of interior China must be open for uninterrupted opium traffic.
The British suffered a defeat at the Taku Forts in June 1859 when sailors, ordered to seize the forts, were run aground in the mud-choked harbor. Several hundred were killed or captured. An enraged Palmerston said: "We shall teach such a lesson to these perfidious hordes that the name of Europe will hereeafter be a passport of fear."
The Destruction of the Yuanmingyuan
|There followed an orgy of indiscriminate plunder in which anything that could not be carted off was destroyed.|
On Oct. 18, British forces were ordered by Lord Elgin - son of the Lord Elgin who removed the marble friezes from Greece’s Parthenon - to inflict a final blow, with fire, as revenge for the Chinese refusal to permit the importation of opium that was devastating their country, though ostensibly for the deaths of some British and Indian prisoners in Chinese captivity.
Because Yuanmingyuan was so vast - roughly five times the size of Beijing’s Forbidden City and eight times that of Vatican City - it took an entire infantry division of nearly 4,500 men, including four British regiments and the 15th Punjabis, many weeks to set it aflame and finally render it to utter destruction.
Gilded beams crashed, porcelain roofs buckled and ash filled the lakes, as so many embers snowed down on Beijing that the entire city seemed on fire, where and the clouds of smoke were so dense they eclipsed the sun.
Upon hearing the news, the ailing 30-year-old Xianfeng emperor vomited blood; less than a year later he was dead.
"It was a sacrifice of all that was most ancient and most beautiful," acknowledged Robert McGhee, chaplain to the British forces and a participant in, and defender of, the destruction. "It is gone, but I do not know how to tear myself from it."
Arguably the greatest concentration of historic treasures in the world, dating and representing a full 5,000 years of an ancient civilisation, were either looted or totally destroyed. And all of this was done to protect the exclusive opium concessions granted to the Jewish Sassoons of Britain, and the revenue they generated for the crown.
God Save the Queen, and God Bless "His Chosen People".
The Yuanmingyuan is an unforgettable shame in the hearts of the Chinese people, and a reminder for the whole world that such destruction of human cultural heritage should not happen again.
You can read more on the Yuanmingyuan:
(1) Jewish Opium and British Imperialism: The Wanton Destruction of China's Yuanmingyuan.
(2) China Remembers a Vast Crime by the West: The Destruction of the Yuanmingyuan in Beijing.
The British and Jewish "Peace Treaties" and the Origin of British Hong Kong
In the new "Peace Treaty" of Oct.25, 1860, the Sassoons (backed by the force of the British military) were assigned rights to a vastly expanded opium trade covering seven-eights of China. England took not only the Hong Kong peninsula as a colony but also large sections of Amoy, Canton, Foochow, Ningbo and Shanghai.
Hong Kong (as a colony) was founded by the British specifically for a life of crime. When Britain gave the Jewish Sassoon family the exclusive franchise to distribute opium in China, the family needed a base of operations for the importing, processing, packaging and distribution. Hong Kong was forcibly "leased" solely for the Sassoon family's opium business.
This was the bloody origin of Hong Kong's 155 years as a British colony.
Readers may not be generally aware of the behind-the-scenes negotiations in London that preceded the return of Hong Kong to China. The "Iron Lady" (perhaps referring to the chastity belt, and perhaps not) Margaret Thatcher, decided at the last minute she wasn't returning Hong Kong to anybody. The word is that her ministers panicked and browbeat her into concession, for fear of starting World War III.
And for sure it might have done. After all of the past humiliation, there is no way China would have accepted a betrayal or default on that agreement. The Chinese government later admitted it would have just moved in with troops and taken Hong Kong back. And you couldn't blame them.
The Origin of British Hong Kong Banking
After the British established Hong Kong as a colony in the aftermath of the Opium Wars, local merchants felt the need for a bank to finance the growing opium trade with China, so they established (by special permit from the British) the Hongkong and Shanghai Banking Corporation - HSBC today - "The World's Bank".
This is the same bank that almost 30 years ago built the world's most expensive building as their head office in Hong Kong - 1 billion US dollars.
The Sassoons Destroyed Everything They Touched
Money for these people was only a tool for making more money, no matter the disasters wrought upon the Chinese - or indeed any other nation.
Sir Albert Sassoon, the eldest of David Sassoon's sons took over the family "business" empire. He constructed huge textile mills in Bombay that paid true slave wages. This early example of the "off-shoring of industries" continued after World War One and ended up putting mills in Lancashire, England out of business with thousands losing their jobs to the cheap labor of the Sassoons in India.
This did not stop Queen Victoria from having Albert knighted in 1872. After all, the Sassoons could prosper only after they had subverted the governance of China, whereupon Britain empowered the Sassoons to destroy and impoverish the people, for the glory of the British Empire.
Solomon Sassoon moved to Hong Kong and ran the family business there until his death in 1894. Later, the entire family moved to England because with modern communications they could operate their financial empire from their luxurious estates in London. They socialized with royalty and Edward Albert. Sassoon married Aline Caroline de Rothschild in 1887 which linked their fortune with that of the Rothschilds. The Queen then also had Edward knighted. All 14 of the grandsons of David Sassoon were made officers during World War One and thus most were able to avoid combat.
David Sassoon became a naturalised British citizen in 1853. He kept the dress and manners of the Baghdadi Jews, but allowed his sons to adopt English manners. His son, Abdullah changed his name to Albert, moved to England, became a Baronet and married into the Rothschild family. All the Sassoons of Europe are said to be descendants of David Sassoon.
The Ubiquitous American Connection . . .
Warren Delano was a senior partner in Russell & Company, whose ships carried the opium that was imposed on China.
The reason Russell & Company were allowed to transport and trade in opium around Canton was that they were a Jewish company and did not interfere with the business of Sassoon's East India Company. The market was large enough for both. Russell & Company got their opium from Afghanistan through a harbor in Turkey.
Delano said later he could not pretend to justify the opium trade on moral grounds, "but as a merchant I insist it has been . . . fair, honorable and legitimate", and "no more objectionable than the importation of wines and spirits to the US."
He returned to America a rich man, and gave his daughter Sara in marriage to a James Roosevelt, the father of Franklin Delano Roosevelt, the American President.
Roosevelt's fortune was inherited from his maternal grandfather Warren Delano. Roosevelt always knew the origin of the family fortune but neither side of the family cared to discuss the source of their great wealth.
The British-protected Sassoon opium trade brought death and destruction to millions and still plagues Asia to this day.
The forcible introduction of opium into China was not some minor event. It extended for much more than 100 years, and totally devastated an entire nation of a billion people, weakening it to the point where it was a walkover for Japan to invade. In addition to the social and financial destruction, and the reversal of China's development, these events led eventually to the civil war and Mao's ascendance, and so much else since.
Nothing else in China's history has had such an impact on what and where China is today. This brutal period of unconscionable imperialism and evil profiteering is surely one of the greatest two or three events in China's 5,000 years of history.
Countless tens of millions of familes were destroyed; fortunes lost, daughters prostituted, production collapsed, the economy crashed. The treasures and heritage of 5,000 years of a peaceful society ravaged by madness and destruction of the British and French. The toll was unimaginable. The British Crown and the Jewish Sassoons conspired to turn an entire nation of people into drug addicts of the worst kind, solely to satisfy their greed and lust for power.
This drug trade totally eviscerated China's social fabric, virtually destroying not only the country but families and all of society. And, by most estimates, the forcible imposition of opium on The Middle Kingdom by Britain, and the clever and brutal marketing by the Sassoon Jews, set back China's development at least 75 years.
And, using their magical technique of putting all of the blame of their sins upon a scapegoat, to this day the Jews claim that the Opium Trade of China was the fault of the British simply because the Sassoons all had British passports. And to this day, many Chinese believe them.
And the British East India Company itself was owned, at least in large part, by these same families - the Rothschilds, the Sassoons, and others.
Any resentment that the Chinese might feel toward the British today, at least due to the imposition of opium, is partially misdirected. A fair share should be directed to these Jewish merchants.
|War financing can be difficult to trace, but it is almost a certainty that much of their financing came from the Jewish bankers who have always financed wars - the Rothschilds, Joseph Schiff and, in this case, the Sassoons - who used their profits from destroying and weakening China to finance the Japanese invasion and further colonisation of China.|
It is popular lore that China welcomed and gave harbor to many Jews during their troubled times in Germany during the Second War, but I have seen no hard evidence that this was the case. It would appear that "China" did not invite, receive or harbor Jews during those periods, that this is yet another common (and deliberate) misconception.
Evidence suggests that the influx of Jews into China was arranged by the Sassoons, the Hardoons, probably Schiff, and other Jewish families, in agreements made with the Japanese military occupation which they were helping to finance. Virtually all of those Jewish immigrants came primarily to Shanghai, which was at the time well outside the control of China's government which had nothing whatever to say about the influx of immigrants there,
Jews or otherwise.